Der findes et 12 ugers studie udført af Werk et al. Studiet er veludført, placebo kontrolleret, dobbelt-blind udført af læger i åben praksis. Der er anvendt relevant statistiske parametre såsom reduktion i vægt og BMI. Der kunne påvises en statistisk og klinisk relevant signifikant effekt for verum gruppen.
Foruden at påvise effekt, viste forsøget at Helianthus er veltolereret, hvilket normalt ikke gælder for præparater med højt indhold af inulin. Her oplever man ofte mavesymptomer som f.eks. oppustethed. Ud fra disse data kan det uddrages, at inulin indholdet ikke er afgørende og at inulin ikke er det hovedaktive stof. Som i så mange andre tilfælde, er der tale om, at effekten stammer fra hele plantens spekter af indholdsstoffer.
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