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Ny energi til aldrende mænd
fra Vitalrådets nyhedstjeneste
Mænd får også hormonmangel
De bliver trætte og triste, mangler kræfter og får seksuelle problemer, men sandsynligvis hjælper carnitin.
Mænd har ingen menopause og deres hormonproduktion ophører ikke på én gang. Derimod aftager produktionen gradvis fra 20-årsalderen, og gennemsnitligt med en procent om året. Når en gennemsnits-mand får udbetalt sin første folkepension, har han mistet ca. halvdelen af sin hormonproduktion. Det er ikke uvigtigt.
Det mandlige kønshormon, testosteron, er afgørende for både den seksuelle adfærd, humøret, evnen til at koncentrere sig, hukommelsen, muskelstyrken og følelsen af fysisk oplagthed.
Negative ændringer på disse områder, kombineret med nedsat hormon-produktion, kaldes – med et dårligt udtryk – andropausen. Det er et stigende problem. Der bliver flere ældre mænd.
For en mand med udtalte symptomer er løsningen naturligvis testosteron.
Hvad gør man, når det er knap så slemt?
Testosteron skal man ikke spøge med. Det forstørrer prostata og kan teoretisk set øge væksten af prostata. Med hensyn til hormontilskud er mænd i samme knibe som kvinder.
Måske er der en redning
Forsøg fra de senere år tyder på, at det simple fysiologiske stof carnitin hjælper på alle symptomer. Carnitin er nødvendigt for forbrændingen af fedt og dermed for dannelsen af energi. Normalt dækkes behovet dels af kosten (mejeriprodukter og kød), dels ved organismens egenproduktion. Sidstnævnte kræver B- og C-vitaminer.
At carnitin vitterligt hjælper på andropause-symptomer illustreres af et italiensk lodtrækningsforsøg fra 2004.
Her fik hver anden af 120 mænd et tilskud af carnitin, mens resten fik en høj dosis testosteron (120 mg testosteron-undecanoat (Restandiol ®) om dagen). Mændene var sådan set fysisk raske. De var ikke-rygere, midt i 60-erne. Men de led af træthed, lettere depression, nedsat sex-lyst og svigtende erektion.
Tre positive forsøg
Forsøget varede et halvt år. Det viste, at både carnitin og testosteron med sikkerhed hjalp på træthed, humør og sex-funktion.
F.eks. kunne man direkte måle, at blodforsyningen til penis blev bedre. Men overraskende viste det sig, at carnitin faktisk virkede bedre end testosteron, både på humør, erektionsevne og generel tilfredshed med sex-funktionen.
Et andet forsøg har vist noget lignende. Her deltog diabetikere, der i mindst otte forsøg med Viagra ikke havde fået erektion. Også dette var et lodtrækningsforsøg. Kombinerede man Viagra (50 mg to gange om ugen) med carnitin, fungerede tre ud af fire igen. Nøjedes man med Viagra, lykkedes det for mindre end halvt så mange.
I et tredje forsøg behandlede man mænd, der var blevet impotente fordi de havde fået fjernet prostata på grund af kræft. Placebopiller (snydepiller) hjalp ikke.
Gav man dem derimod mændene Viagra (100 mg ved behov), kunne hver anden berette om tilfredsstillende samleje.
Men med en kombination af Viagra og carnitin lykkedes det for næsten alle (28 af 32).
Det lader i høj grads til, at dette helt naturlige stof kan hjælpe vældigt mange aldrende mænd.
Carnitin er ufarligt, men hvorfor virker det?
En del af forklaringen er nok, at mange mænd med alderen får en veritabel mangel på stoffet. Kønshormoner stimulerer organismens dannelse af carnitin. Ved mangel på kønshormon aftager carnitin-produktionen. Det må kunne give problemer, selv om det næppe er hele forklaringen.
Den præcise sammenhæng, bl.a. hvorfor carnitin øger blodtilstrømningen til penis, kan man kun gisne om.
Der mangler viden, også om hvor meget carnitin man tåler i det lange løb. I de nævnte forsøg er brugt fire gram (2 x 2) om dagen. Det ser ud til at være risikofrit, men er man nøjeregnende, er der på langt sigt kun dokumentation for sikkerhed ved op til halvdelen af denne dosis.
Referencer
1. Cavallini G. et al. Carnitine versus androgen administration in the treatment of sexual dysfunction, depressed mood, and fatigue associated with male aging. Urology. 2004 Apr;63(4):641-6 2. Cavallini G et al. Acetyl-L-carnitine plus propionyl-L-carnitine improve efficacy of sildenafil in treatment of erectile dysfunction after bilateral nerve-sparing radical retropubic prostatectomy. Urology. 2005 Nov;66(5):1080-5 3. Gentile V, et al. Preliminary observations on the use of propionyl-L-carnitine in combination with sildenafil in patients with erectile dysfunction and diabetes. Curr Med Res Opin. 2004 Sep;20(9):1377-84. Department of Urology U Bracci, University La Sapienza, Rome, Italy. 4. Mooradian AD et al. Management of the cardinal features of andropause. Am J Ther. 2006 Mar-Apr;13(2):145-60. 5. Hathcock JN, Risk assessment for carnitine. Regul Toxicol Pharmacol. 2006 Oct;46(1):23-8. Epub 2006 Aug 9
Vitalrådets nyhedstjeneste 10. oktober 2006
Yderligere oplysninger: Speciallæge Claus Hancke Speciallæge Niels Hertz Vitalrådet – www.vitalraadet.dk Lyngby Hovedgade 37 2800 Kgs. Lyngby Tlf.: 45 88 09 00
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