Synonymer: P. niruri, P. fraternus
Indisk navn: Bahupatra
Familie: Euphorbiaceae
Droge: Blade, urt
Beskrivelse
Et-årig plante, op til 60 cm høj. Små blade arrangeret i to rækker. Vokser i de varme dele af Indien og Sydøstasien. Sydindiens vigtigste urt i behandlingen af gulsot.
Aktive indholdsstoffer
Lignaner (bl.a. phyllanthin og hypophyllanthin), flavonoider og alkaloider.(1)
Farmakologi
Lignaner virker leverbeskyttende in vitro og nedsætter fedtaflejring i leveren, hjernen, nyrene og hjertet forårsaget af alkoholmisbrug. Drogen inaktiverer hepatitis B virus ved, in vitro, at binde til virusantigener.(1, 2)
Egenskaber
Antivirus, leverbeskyttende, blodsukkersænkende, vanddrivende, astringerende, let afførende, bitter tonic.(1, 2, 3)
Indikationer
- Leversygdomme
Virusleversygdomme, bl.a. både akut og kronisk leverinflammation. Kronisk, aktiv leverinflammation (autoim munsygdom forårsaget af virus). Hepatitis B.(5, 6) - Virussygdomme
Kan muligvis også anvendes imod andre virussygdomme. - Traditionelle
indikationer Anvendes traditionelt imod sukkersyge, gonoré, dysenteri, urinvejssygdomme og gulsot, forstoppelse, dårlig fordøjelse, feber. Den friske saft blandes med olie i udvortes behandling af sår, kløe, fnat og andre hudsygdomme.(3)
Kontraindikationer
Ingen kendte.
Bivirkninger
Ingen bivirkninger ved anbefalet dosering.
Toksicitet
Ingen giftvirkninger ved anbefalet dosering.
Dosering
Tørret droge: 0,5‑1 g tre gange daglig.(2) Ekstrakt (1:2) i 45% alkohol: 15‑40 ml ugentlig.(4)
Kombinationsforslag
Phyllanthus amarus kan blandes med Cynara scolymus, Taraxacum officinalis, Salvia miltiorrhiza, Silybum marianum og Bupleurum falcatum i behandlingen af leversygdomme.
Referencer
1. Bone, K., Burgess, N., McLeod, D., How To Prescribe Herbal Medicines, 2.ed. Warwick: MediHerb Ltd., (1992) 2. Bone, K., Post Graduate Course in Phytotherapy, Warwick: MediHerb (1990) 3. Kapoor, L. D.:CRC Handbook of Ayurvedic medicinal Plants,Boca Raton: CRC Press (1990) 4. MediHerb, 31st May 1995 Dose Report, ikke udgivet 5. Wang, M. et al: J Lab and Clin Med, 126, 350-2 (1995) 6. Blumberg, B.: Phylanthus amarus and the Treatment of Hepatitis B Virus, in New Drugs from Natural Substances
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