Bakteriel vaginose er den mest almindeligt forekommende vaginale infektion blandt gravide kvinder, og den kan resultere i en række forskellige symptomer, herunder urinvejsinfektion, underlivsbetændelse, abort og lav fødselsvægt. En ny kinesisk metaanalyse udført af forskere fra Weifang Medical University i Shandong, Kina, viser, at risikoen for dette problem er markant større hos kvinder, der mangler D-vitamin.
Af Bjørn Falck Madsen
Forskerne kiggede på data fra sammenlagt 14 videnskabelige undersøgelser, der sammenlignede D-vitaminniveau og forekomst af bakteriel vaginose hos i alt 4.793 gravide kvinder. De fandt, at hos dem med mangel på D-vitamin, var risikoen hele 54 pct. højere end hos kvinder, som ikke havde mangel på vitaminet.
Ifølge forskerne bag metaanalysen er det D-vitamins regulerende rolle i immunforsvaret, som er vigtig i denne forbindelse. Vitaminet er i stand til at udløse antimikrobielle peptider som cathelicidin, der har antiinflammatoriske egenskaber. Samtidig virker D-vitamin ved at hæmme kroppens produktion af proinflammatoriske cytokiner.
Kilde: Frontiers in Nutrition, november 2022
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