Synonymer: Helxine multiflorum, Pleuropterus cordatus
Dansk navn: Mangeblomstret pileurt
Kinesiske navne: He-shou-wu, Ho-shou-wu
Engelske navne: Fo-ti, Chinese cornbind
Familie: Polygonaceae
Droge: Rod
Beskrivelse
Flerårig klatreplante, op til 2 meter lange, snoede ranker. De tykke, træagtige rodstokke kan veje op til 3 kg. Multiflorum henfører til plantens mangfoldige bittesmå blomster. Vokser på sletter, vejkanter, skovkanter, mellem klipper i bjergegne og bambubuske overalt i Kina undtagen de nordøstlige dele. Den friske rod høstes om foråret eller sommeren når den er 3 til 4 år gammel. Roden forarbejdes for at eliminere bivirkninger forbundet med anvendelse af roden i dens naturlige tilstand. Den tørrede rod koges gennem længere tid med et afkog af sorte bønner i et kar, der ikke må bestå af metal. Afkoget laves ved at koge de sorte bønner i fire timer, filtrere væsken fra, gentage processen med mere frisk vand, og til sidst blande de to afkog og hælde det over Polygonum multiflorum roden, som koges indtil al bønnevæsken er blevet absorberet.(1) Den forarbejdede rod kaldes Zhi-he-shou-wu.
Aktive indholdsstoffer
Tetrahydroystilben glykosid, antrakinoner, garvestoffer, fosforlipider (bl.a. lecitin), sporstoffer.(1, 2)
Egenskaber
Nervestyrkende, antioxidant, hæmmer alderdomsprocessen, nedsætter kolesterol, bitter tonic.
Traditionelle egenskaber: Bitter, sød, astringerende og varmende. Zhi-he-shou-wu toner livsenergien og blodet, og styrker muskler, sener og knogler.
Farmakologi
Hæmmer udviklingen af arteriosklerose i rotter med en kolesterolrig diæt (nedsætter ikke altid niveauet af kolesterol)2, nedsætter niveauet af lipidperoxyd (mere effektivt end vitamin E) og forlænger levetiden for senile vagtler.(3, 4) Hæmmer alderdomsprocessen ved af hæmme monoamio-oxydase (MAO-B) og opretholde superoxid dismutase niveauet (5), hæmmer cancer i mus, hæmmer visse kræftfremkaldende stoffer (benzo-alfa-pyren)(6), hæmmer kemikalieforårsaget ophobning af triglycerider i muselever, hæmmer leverforstørrelse forårsaget af tetraklor-kulstof.(7) Kliniske forsøg har vist, at Polygonum multiflorum kan sænke blodkolesterol (62% havde signifikant reduktion i blodkolesterol) og fremmer bedre søvn i patienter, der lider af neurathenia (nervøs udmattelse).(2)
Indikationer
- Hjertekredsløbet
Forhøjet blodkolesterol. (8) - Nervesystemet
Neurasthenia med søvnbesvær, epilepsi, nervesmerte og schizofreni.(9) - Alderdom
Hæmmer for tidlig alderdom, fremmer levetiden, generelt styrkende i alderdommen.(9) - Andre indikationer
Svagt bindevæv, tinnitus, svimmelhed og sløret syn.(9) - Traditionelle indikationer
Yin-mangel i leveren og nyrerne, svimmelhed, søvnbesvær, grå hår, smerter i lænden og knæet, svag ejakulation, udflåd fra skeden, tuberkulose i lymfeknuder, hudsygdomme som bylder. He-shou-wu er en af de mest anvendte styrkende urter i den kinesiske urtemedicin.
Kontraindikationer
Ingen kendte.
Bivirkninger
Den friske rod kan forårsage diarre, mavekneb, kvalme og opkastning. Overdosering kan forårsage hududslæt og følelsesløshed i benene.(1)
Toksicitet
Ingen giftvirkninger ved anbefalet dosering.
Dosering
Tørret droge: 1,3-2,6 g, 3 gange daglig.(9) Ekstrakt (1:2) i 25% alkohol: 50-100 ml ugentlig.(10) Forhøjet blodkolesterol: op til 160 ml ugentlig.(9)
Kombinationsforslag
Kan blandes med Cynara scolymus i behandlingen af forhøjet blodkolesterol, Astragalus membranaceus for at hæmme for tidlig alderdom, med Bacopa monniera og Schisandra chinesis for at styrke nervesystemet.
‘Referencer
1. Foster, S. Og Chongxi, Y. Herbal Emissaries, s. 79-85, Healing Arts Press, Vermont (1992) 2. Chang, H M og But, P P Pharmacology and Application of Chinese Materia Medica, Vol. 1, World Scientific, Singapore (1987) 3. Tang, W og Eisenbrand, G Chinese Drugs of Plant Origin, Springer Verlag, Berlin (1992) 4. Wang, W et al Chin J Integ Trad West Med, 8, 223, (1988), i Abstract Chin Med , 2, 307, (1988) 5. Hong, C Y et al Am J Chin Med, 22, 63, (1994) 6. Deng, W L et al Chin Trad Herb Drugs, 18, 138, (1987) i Abstract Chin Med , 2, 84, (1988) 7. Horikawa, K et al Mutangenesis 9, 523, (1994) 8. Liu, C et al Chung-Kuo Chung Yao Tsa Chih, 17, 595, 639 (1992) 9. Bone, K., Chinese and Ayurvedic Herbs, MediHerb, Warwick (1995) 10. MediHerb, 31st May 1995 Dose Report, Ikke udgivet
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